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Pulmonary Manifestations in Adolescents With Inflammatory Bowel Disease.

TitlePulmonary Manifestations in Adolescents With Inflammatory Bowel Disease.
Publication TypeJournal Article
Year of Publication2020
AuthorsBarfield E, Deshmukh F, Slighton E, Lentine J, Lu Y, Ma X, Christos PJ, Sockolow RE, Loughlin G, Pillai S
JournalClin Pediatr (Phila)
Pagination9922820910821
Date Published2020 Mar 07
ISSN1938-2707
Abstract

. The available literature on pulmonary disease in pediatric inflammatory bowel disease is limited. We evaluated the prevalence of pulmonary manifestations in pediatric inflammatory bowel disease and their association with disease severity. . Patients completed the St. George's Respiratory Questionnaire (SGRQ), a self-reported measure of quality of life in patients with pulmonary disease. Chart review provided demographic information and Pediatric Crohn's Disease Activity Index (PCDAI) and Pediatric Ulcerative Colitis Activity Index scores. Regression models were utilized to evaluate associations between SGRQ score and clinical risk factors. . The prevalence of pulmonary manifestations was 9.62% (95% confidence interval = 5.48% to -15.36%). PCDAI scores in Crohn's disease patients with pulmonary symptoms were significantly higher (SGRQ mean = 10.71 ± 10.94) than in patients without such symptoms. SGRQ score was also higher in patients with indeterminate colitis (8.64, 95% confidence interval = 0.72-16.57, = .03), when compared with Crohn's disease. . Additional investigations including pulmonary function tests and imaging could provide further insight into this issue.

DOI10.1177/0009922820910821
Alternate JournalClin Pediatr (Phila)
PubMed ID32146830
Division: 
Biostatistics
Category: 
Faculty Publication