|Title||Reintervention and Survival After Limited Lung Resection for Lung Cancer Treatment in Australia.|
|Publication Type||Journal Article|
|Year of Publication||2019|
|Authors||Tran B, Sedrakyan A, Flynn P, Altorki N, Jorm L, Wright G|
|Journal||Ann Thorac Surg|
|Date Published||2019 May|
BACKGROUND: To investigate the risk and predictors of reintervention (surgery or radiotherapy) after limited resection for lung cancer.
METHODS: A population-based, all-inclusive study using linked data from the New South Wales Admitted Patient Data Collection and Death Register included all patients undergoing limited resection for lung cancer between July 1, 2002, and March 31, 2014. Univariate and adjusted competing risk analyses were used to estimate the effect of potential factors for risk of reintervention within 6 months and 24 months of the initial surgery.
RESULTS: The overall 5-year survival for lung cancer patients undergoing limited lung resection was 52% (49% to 54%); for patients aged 70 years or more, the survival rate was 44% (40% to 47%). Reintervention occurred in 6.2% by 6 months and 11.3% by 24 months after the surgery. Younger age, surgery in private hospitals, and fewer comorbidities were independently associated with increased risk of reintervention. Patients who had the surgery performed in high surgical volume hospitals had 49% lower risk of reintervention within the first 6 months (95% confidence interval: 0.30 to 0.85). The effect of hospital surgical volume was attenuated by 24 months (hazard ratio 0.87, 95% confidence interval: 0.60 to 1.28). Patients undergoing reintervention within 6 months or 24 months had a twofold (1.52 to 2.57) and 2.3-fold (1.89 to 2.83) increased risk of death, respectively.
CONCLUSIONS: The reintervention rate within 6 or 24 months of initial limited lung cancer resection was modest, but there was considerable variation among hospitals. Reintervention was not a benign event and was associated with lower survival in an Australian population.
|Alternate Journal||Ann. Thorac. Surg.|
Reintervention and Survival After Limited Lung Resection for Lung Cancer Treatment in Australia.
Submitted by chz4003 on August 12, 2019 - 1:38pm
Comparative Effectiveness & Outcomes Research