Artificial Intelligence Pathway

Course Director: Yunyu Xiao, PhD
4 credits

Health informatics is the body of knowledge that concerns the acquisition, storage, management and use of information in, about and for human health, and the design and management of related information systems to advance the understanding and practice of healthcare, public health, consumer health and biomedical research. The discipline of health informatics sits at the intersection of several fields of research – including health and biomedical science, information and computer science, and sociotechnical and cognitive sciences. In recent years we have witnessed how the collection, storage and usage of digital health data has exponentially grown. Increases in the complexity of health information systems have driven growth in demand for a specialized workforce. This course introduces the field of health informatics and provides students with the basic knowledge and skills to pursue a professional career in this field and apply informatics methods and tools in their health professional practice.

Course Director: Faculty
3 credits

Informatics innovations have their desired impact only when they have high quality, are highly usable, are integrated into their organizational setting, and are widely adopted and used. That makes it critical for informatics students to understand not only how informatics innovations work, but also the users and settings in which they are used. Students will learn methods and models for: measuring data and system quality; assessing and predicting technology adoption (what makes technology sticky?); improving humancomputer interaction via human factors engineering; understanding organizational and systemic challenges in the real world; influencing patients’ health behavior and decisions; and assessing quality, safety, and cost outcomes using health services research study designs. In this mixed methods course, students will gain experience using both quantitative and qualitative methods.

Course Director: Faculty
3 credits

Introduces students to a variety of analytic methods for health data using computational tools. The course covers topics in data mining, machine learning, classification, clustering and prediction. Students engage in hands-on exercises using a popular collection of data mining algorithms.

Course Director: Faculty
2 credit

This is the culminating capstone course of all masters-level graduate education programs. It has two aims: (1) helping students to discover and develop new and effective ways of managing and working together with all the stakeholders within the healthcare field and (2) helping accelerate a student's development of 12 the context awareness, integrative management, and industry skills that are needed to lead in a rapidly changing healthcare sector. This capstone course puts students in a new organization, one they don’t already know well, and gives them the chance to practice hitting the ground running. This culminating course provides a deeper preparation for the next stages of a student's career. The capstone project will last the entire year: the first term involves matching students with the right project, the second term has students working with their client, and the third term consists of a detailed report and final presentation in front of the client as well as faculty and fellow classmates

Course Director: Chang Su, PhD
3 credits

In addition to technical, programming and analytical skills, healthcare informaticians and data scientists need clinical domain expertise to understand and interpret real world data and analytical findings and to communicate effectively with healthcare practitioners and investigators.  This course is designed to equip informaticians with a foundational understanding of key concepts in clinical medicine, especially as they relate to the collection, application and interpretation of real world data toward clinical phenotypes and predictive analytics.   Students will learn the fundamentals of the cardiovascular, gastrointestinal, respiratory, hematological, endocrine, neurological, musculoskeletal, psychiatric, and renal systems and how diseases in these body systems are reflected in subjective and objective measures collected through patient reports, clinical observations, laboratory tests and ancillary studies.  Students will understand the clinicians approach to ordering tests to evaluate for the presence of disease.  They will also learn about the variety and classification of pharmacological therapies, the context and rationale for starting and stopping medications, and their intended and unintended effects on body systems.  Students will also learn how the physical and social environment in which patients live may impact the recognition and severity of illness, as well as  the timing, approach and outcomes of care. Students will be introduced to differentiated care in the management of different patient specialties, including pediatrics and geriatrics.

Course Director: Lisa Kern MD, MPH
3 credits

The goal of this course is to educate students about the complexity and nuances of healthcare delivery. The course will be especially useful for non-clinicians who intend to go into fields that will require a detailed understanding of healthcare. Class sessions will not summarize healthcare; rather, they will analyze healthcare – through themes such as people, time, money, communication, uncertainty, and others. Students will come away from the course with a deeper appreciation of why it is difficult to change healthcare. They will then be able to anticipate the intended and unintended consequences of interventions and policies that they and others might implement.

Course Director: Arindam RoyChoudhury, PhD
4 credits

An introduction to the fundamentals of biostatistics with primary emphasis on understanding of statistical concepts behind data analytic principles. This course will be accompanied with a Stata lab to explore, visualize and perform statistical analysis with data. Lectures and discussions will focus on the following: exploratory data analysis; basic concepts of statistics; construction of hypothesis tests and confidence intervals; the development of statistical methods for analyzing data; and development of mathematical models used to relate a response variable to explanatory or descriptive variables.

Course Director: Yiye Zhang, PhD
3 credits

Database systems are central to most organizations’ information systems strategies. At any organizational level, users can expect to have frequent contact with database systems. Therefore, skill in using such systems – understanding their capabilities and limitations, knowing how to access data directly or through technical specialists, knowing how to effectively use the information such systems can provide, and skills in designing new systems and related applications – is a distinct advantage and necessity today. The Relational Database Management System (RDBMS) is one type of database systems that are most often used in healthcare organizations and is the primary focus of this course. An overview of the non-relational database structure will also be given using Python programming language to provide a fuller picture of the current data management landscape. Further, to provide students with opportunities to apply the knowledge they learn from the lectures, various homework assignments, lab assignments, an exam, and a database implementation project will be given.

Course Director: Faculty
3 credits

This is the culminating capstone course of all masters-level graduate education programs. It has two aims: (1) helping students to discover and develop new and effective ways of managing and working together with all the stakeholders within the healthcare field and (2) helping accelerate a student's development of the context awareness, integrative management, and industry skills that are needed to lead in a rapidly changing healthcare sector. This capstone course puts students in a new organization, one they don’t already know well, and gives them the chance to practice hitting the ground running. This culminating course provides a deeper preparation for the next stages of a student's career. The capstone project will last the entire year: the first term involves matching students with the right project, the second term has students working with their client, and the third term consists of a detailed report and final presentation.

Course Director: Chengxi Zang, PhD
3 credits

The course “Python for Health AI” is designed for advanced students and clinicians seeking to develop programming expertise in healthcare applications. This course provides hands-on experience with Python, Pytorch, data science/machine learning libraries, LLM and agents techniques, focusing on real-world health data, including EHRs, medical imaging, and clinical text. Participants will explore AI models for disease prediction, causal inference, and natural language processing etc. The course emphasizes practical implementation, from preprocessing messy health data to deploying AI models in clinical settings. Capstone projects will apply AI to real-world health challenges.

Course Director: Marianne Sharko MD, MS
3 credits

Prerequisite: Introduction to Health Informatics
Clinical information systems such as electronic health records are central to modern healthcare. This course introduces students to the complex infrastructure of clinical information systems, technologies used to improve healthcare quality and safety (including clinical decision support and electronic ordering), and policies surrounding health information technology.

Course Director: Yifan Peng, PhD
3 credits

This course introduces students to the field of natural language processing (NLP), applied to the health domain. NLP focuses on text data, which lacks the structure of conventional tabular data. In the health domain text is abundant in electronic health records, the medical literature and on the Web. Important applications of NLP include information extraction (pulling facts out of text) and information retrieval (searching through a collection of texts). The course presents methods for working with text: identifying the elements (words and symbols), recognizing sentence boundaries, parsing syntactic structures, assigning meaning, and establishing the structure of the discourse as a whole. The students build skills with these methods through laboratory work.

Course Director: Faculty
3 credits

This is the culminating capstone course of all masters-level graduate education programs. It has two aims: (1) helping students to discover and develop new and effective ways of managing and working together with all the stakeholders within the healthcare field and (2) helping accelerate a student's development of the context awareness, integrative management, and industry skills that are needed to lead in a rapidly changing healthcare sector. This capstone course puts students in a new organization, one they don’t already know well, and gives them the chance to practice hitting the ground running. This culminating course provides a deeper preparation for the next stages of a student's career. The capstone project will last the entire year: the first term involves matching students with the right project, the second term has students working with their client, and the third term consists of a detailed report and final presentation in front of the client as well as faculty and fellow classmates.

Course Director: Fei Wang, PhD
3 credits

Prerequisite: Artificial Intelligence in Medicine I
This class will teach students more advanced topics on AI in medicine. It requires students to have taken the AI in medicine I class. The contents of the class cover generalizability of AI models, computational fairness, model interpretation and explanation, privacy and security, federated learning, multi-modal learning, generative AI, causal inference, target trial emulation. The students will be asked to do a final project with teams based on the contents taught in the class, and python programming will be needed for doing the project.

Course Director: Faculty
3 credits

In a modern healthcare system, exchange of clinical data across multiple stakeholders – between healthcare organizations, between providers and patients, and among agencies and governmental entities – is pivotal. Health information standards provide the “backbone” to achieve uniform data interoperability and exchange across multiple heterogeneous systems. This course will introduce various existing and emerging clinical data modeling, terminology and knowledge representation standards that are part of Meaningful Use Regulations, and discuss scenarios and use cases where the standards have been applied for routine clinical practice and research.

Course Director: Faculty
3 credits

Consumer health informatics (CHI) is the study of consumer information needs and technologies that provide consumers with the information they need to be more engaged in self-care and healthcare. This introductory CHI course will present an overview of theories of health and information behavior; key concepts and terminology; and main application domains. We will explore how health behavior theories 8 provide a framework for explaining consumers’ health behaviors and how CHI tools that are built with a theoretical foundation can promote health behavior change. The course will cover CHI applications in major application domains including electronic patient portals, mobile health (mHealth), and telehealth. Students will learn how to assess end-user needs and technological practices of potential users who experience health information and technological disparities. Students will also learn how to design for endusers, evaluate CHI applications and research.

Course Director: Faculty
3 credits

This course provides an overview of implementation science and examines ethical, methodological, and practical challenges in the use of artificial intelligence (AI) in healthcare. It focuses on the safe and effective development, evaluation, and implementation of predictive models, large language models, and generative AI systems in real-world clinical settings. 

The course introduces frameworks for evaluating AI systems using the principles of fairness, appropriateness, validity, effectiveness, and safety (FAVES), along with performance metrics, generalizability, and robustness across populations and healthcare environments. It examines sources of bias, distribution shift, and unintended consequences, and explores ethical issues through the lens of autonomy, beneficence, nonmaleficence, and justice. Students will analyze trade-offs between performance, fairness, privacy, and safety, and consider the implications for different stakeholders, including patients, providers, and health systems.

The course also covers key concepts in data governance, privacy, and human factors, as well as implementation science frameworks such as Diffusion of Innovation, RE-AIM, and PRISM. Emphasis is placed on translating AI models into practice, including workflow integration, monitoring, and real-world deployment challenges. In addition, the course introduces emerging topics such as large language models and agentic AI systems for clinical decision support and healthcare operations.

We will invite experts in the field to provide guest lectures and to lead student workshops within their areas of expertise.

1-3 credits