|Title||Why Maximizing Quality-Adjusted Life Years, rather than Reducing HIV Incidence, Must Remain Our Objective in Addressing the HIV/AIDS Epidemic.|
|Publication Type||Journal Article|
|Year of Publication||2019|
|Authors||Nosyk B, Min JEun, Zang X, Feaster DJ, Metsch L, Marshall BDL, Del Rio C, Granich R, Schackman BR, Montaner JSG|
|Journal||J Int Assoc Provid AIDS Care|
|Date Published||2019 Jan-Dec|
With efficacious behavioral, biomedical, and structural interventions available, combination implementation strategies are being implemented to combat HIV/AIDS across settings internationally. However, priority statements from national and international bodies make it unclear whether the objective should be the reduction in HIV incidence or the maximization of health, most commonly measured with quality-adjusted life years (QALYs). Building off a model-based evaluation of HIV care interventions in British Columbia, Canada, we compare the optimal sets of interventions that would be identified using HIV infections averted, and QALYs as the primary outcome in a cost-effectiveness analysis. We found an explicit focus on averting new infections undervalues the health benefits derived from antiretroviral therapy, resulting in suboptimal and potentially harmful funding recommendations.
|Alternate Journal||J Int Assoc Provid AIDS Care|
|PubMed Central ID||PMC6457342|
|Grant List||R01 DA041747 / DA / NIDA NIH HHS / United States|
Why Maximizing Quality-Adjusted Life Years, rather than Reducing HIV Incidence, Must Remain Our Objective in Addressing the HIV/AIDS Epidemic.
Submitted by chz4003 on August 12, 2019 - 1:20pm
Comparative Effectiveness & Outcomes Research